Actionable for Doctors,
Understandable for Patients.

Through PRENITA TM, Bioserve offers a range of pre and post natal screening tests that provide accurate results with actionable insights, which help the clinician to provide the best outcome to the patients.

Chromosomal abnormalities in the foetus constitute one of the leading causes of stillbirth and birth of infants with malformations.

Prenatal testing identifies chromosomal abnormalities at a very early stage, enabling the expecting parents in better management of healthcare conditions. Early intervention in such cases is of prime importance.

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PRENITA

TM

NIPT

Non-invasive Prenatal Testing

PRENITA TM NIPT is an advanced non-invasive prenatal screening test that analyses the developing baby’s DNA, circulating in the mother’s blood. It checks for genetic conditions that could affect the baby’s health.

Features

Simple

Only requires 8-10ml of maternal blood sample.

Safe

Non invasive and safe for both mother and fetus.

Early Detection

Can be performed as early as 10th week of pregnancy.

Comprehensive

Includes information on all 23 pairs of chromosomes.

Accurate

Higher sensitivity and specificity.

Fast

Results are provided within 10 working days.

NIPT SCREENS FOR

Chromosomal Aneuploidies Screened

Trisomy 13: Patau syndrome

Trisomy 18: Edward Syndrome

Trisomy 21: Down syndrome

XXY: Klinefelter syndrome

X0: Turner syndrome

XYY: Jacob syndrome

XXX syndrome

Microdeletions Screened

DiGeorge syndrome

1p36 deletion syndrome

Angelman/Praderwilli syndrome

Cri-du-chat syndrome

Wolf Hirschhorn syndrome


additional services

Genetic Counseling for expecting parents.

Confirmatory Tests to follow up screening for at-risk pregnancies.

FAQs

Q. What is PRENITA TM NIPT?

PRENITA NIPT is a Non-Invasive Prenatal Screening Test offered by Bioserve. It’s simple, fast, reliable, and most importantly, it’s safe! As the name suggests, it’s a non-invasive test done to rule out any genetic issues the baby might have. Our genetic system consists of DNA of which the baby receives one set from the mother and the other set from the father. During pregnancy, bits of the baby’s DNA enter the mother’s blood. Thus, by extracting the mother’s blood these DNA bits from the baby can be identified and tested upon.

Q. What does PRENITA TM NIPT convey?

NIPT is a screening test that provides a checklist and score card to the above mentioned genetic conditions (Aneuploidyand Microdeletion ). An indication of Low risk or High Risk helps you to determine the next line of action to ensure your baby’s condition. This may include further tests to assess and determine the issue.

Q. If NIPT result says that it’s a low risk for the detected aneuploidies, does it mean that an Ultrasound scan and maternal serum screening can be avoided?

NIPT  does not screen for certain defects like open neural tube defects and cannot predict late pregnancy complications like pre-eclampsia. Thus, maternal serum screening or Ultrasound cannot be avoided.

Q. If my first child is affected by Down Syndrome will my second child also be affected?

Downs Syndrome is a condition wherein there is an extra set of chromosomes (3 copies of chromosome 21 instead of 2 copies) in the child. This kind of Aneuploidy is a result of random errors during DNA replication, either at conception or during the initial stages of pregnancy. It is not an inherited genetic condition and thus cannot aect the second child.

Q. What are the limitations of the test?

It is a screening test and not a diagnostic test, and chromosomal abnormalities such as unbalanced translocations, deletions, and duplications cannot be detected by NIPT.

Q. What are the plausible reasons for error in NIPT?

- Early gestational age.
- Placental mosaicism. 
- Maternal obesity Multiple pregnancies and vanishing twins. 
- Maternal conditions like mosaicism or malignant disease or transplantation.

Q. Are there any additional tests offered by PRENITA TM?

If the NIPT test reveals a High-Risk score, confirmatory testing on invasive samples (CVS and amniotic fluid) must be performed. Diagnostic tests like Microarray, QFPCR, and MLPA are also offered under PRENITA as follow ups for NIPT.
Furthermore, we care about the overall well-being of an expectant mother thus providing personalized counselling for the mother to discuss results and its impacts on her baby. An expert team of counsellors are dedicated to ensure that every doubt is cleared and help provided.

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